[Clinical aspects of hypertension in children with aortic coarctation]

Silvia Mătăsaru1, Doina Felea, Cristina Maftei

  • 1Disciplina Medicină Generală/Familie-copii, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.

Insights

Surgical repair of aortic coarctation significantly improves blood pressure in children. Most patients achieve normal blood pressure within a year post-operation, though persistent hypertension may indicate underlying issues.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Hypertension Research

Context:

  • Aortic coarctation is a congenital heart defect requiring surgical intervention.
  • Pre-operative hypertension is a common finding in children with aortic coarctation.
  • Monitoring blood pressure post-repair is crucial for long-term outcomes.

Purpose:

  • To evaluate the effectiveness of surgical repair in normalizing blood pressure in pediatric patients with aortic coarctation.
  • To compare post-operative blood pressure readings with pre-operative values and normal age-matched standards.
  • To identify factors associated with persistent hypertension after surgical correction.

Summary:

  • This study analyzed blood pressure in 26 children (aged 1-18 years) before and after surgical repair of aortic coarctation.
  • All pre-operative patients exhibited hypertension, ranging from high-normal to severe.
  • Post-surgery, 75% of children had normal blood pressure within one year, while 25% continued to experience hypertension.

Impact:

  • Surgical repair of aortic coarctation leads to significant blood pressure normalization in the majority of pediatric patients.
  • Persistent severe hypertension post-operatively suggests the need for further investigation into unrecognized underlying conditions.
  • These findings underscore the importance of timely surgical intervention and long-term blood pressure monitoring in managing aortic coarctation.
Abstract

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...