Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Developmental gene network analysis.

Roger Revilla-i-Domingo1, Eric H Davidson

  • 1Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

The International Journal of Developmental Biology
|February 6, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular circadian rhythms are robust in marine annelids lacking rhythmic behavior.

PLoS biology·2024
Same author

Tracing the history of cell types.

eLife·2023
Same author

Characterization of cephalic and non-cephalic sensory cell types provides insight into joint photo- and mechanoreceptor evolution.

eLife·2021
Same author

A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity.

Science advances·2020
Same author

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids.

Development (Cambridge, England)·2018
Same author

Developmental effector gene regulation: Multiplexed strategies for functional analysis.

Developmental biology·2018
Same journal

Spatiotemporal dynamics of lineage-specific epithelial maturation in the developing mouse stomach.

The International journal of developmental biology·2026
Same journal

Dynein axonemal assembly factors (<i>dnaaf</i>) 5 and 9 are expressed in ciliated organs of zebrafish embryos.

The International journal of developmental biology·2026
Same journal

A chloroquine sensitivity gradient induces tissue regeneration and maintenance phenotypes in planarians.

The International journal of developmental biology·2026
Same journal

Sialylated glycoproteins and sialyltransferases involved in mesoderm-derived organ formation during embryogenesis.

The International journal of developmental biology·2026
Same journal

The <i>Hydra</i> FGF family - dispersed across the genome and expressed locally.

The International journal of developmental biology·2026
Same journal

Correction: Inhibition of COX2 impairs angiogenesis and causes vascular defects in developing zebrafish embryos.

The International journal of developmental biology·2025
See all related articles

Regulatory elements control gene expression during development. This study models sea urchin endomesoderm development, revealing how cis-regulatory interactions refine patterns and stabilize cell fates, offering insights into evolutionary changes in body plans.

Area of Science:

  • Developmental Biology
  • Systems Biology
  • Evolutionary Developmental Biology

Background:

  • Gene expression is regulated by cis-regulatory elements.
  • Understanding developmental gene networks is crucial for studying evolution.
  • The endomesoderm specification in sea urchins involves complex regulatory interactions.

Purpose of the Study:

  • To analyze a model of cis-regulatory interactions for sea urchin endomesoderm specification.
  • To understand how cis-regulatory elements control developmental processes.
  • To explore the role of developmental gene networks in morphological evolution.

Main Methods:

  • Computational modeling of cis-regulatory networks.
  • Analysis of gene expression patterns.

Related Experiment Videos

  • Comparative analysis of cis-regulatory interactions between species.

    • Main Results:

    • The model demonstrates cis-regulatory control over gene expression, pattern refinement, and state stabilization.
    • Developmental progressivity is linked to cis-regulatory interactions.
    • Comparative analysis with starfish reveals conserved and divergent regulatory mechanisms.

    Conclusions:

    • Cis-regulatory interactions are fundamental to developmental processes and their evolution.
    • Developmental gene network analysis provides insights into morphological diversification.
    • Comparing regulatory networks aids understanding of developmental program evolution.