Related Experiment Video

Updated: Oct 13, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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[Stress-induced bundle-branch block]

H Borer1, B Martina

  • 1Medizinische Universitäts-Poliklinik, Departement Innere Medizin, Kantonsspital Basel.

Schweizerische Medizinische Wochenschrift
|December 26, 1992
PubMed

Insights

Exercise-induced bundle branch block (BBB), particularly right BBB, signals a high risk for underlying coronary heart disease. Noninvasive methods may miss this critical link, necessitating further cardiac investigation.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Diagnostic Imaging

Background:

  • Bundle branch block (BBB) can be a sign of underlying heart conditions.
  • Exercise stress testing is a common noninvasive method for diagnosing coronary artery disease.

Observation:

  • Two patients presented with exercise-induced bundle branch block (BBB).
  • Coronary heart disease was not diagnosed by standard noninvasive techniques in these patients.

Findings:

  • Exercise-induced BBB, especially right BBB, is strongly associated with coronary heart disease.
  • The presence of exercise-induced BBB warrants an intensive search for coronary heart disease.

Implications:

  • Clinicians should consider coronary heart disease in patients with exercise-induced BBB, even with negative noninvasive tests.
  • Further investigation may be needed to confirm coronary heart disease in these cases.
  • This association highlights the importance of recognizing exercise-induced BBB as a potential cardiac risk indicator.

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