Related Experiment Videos
Menstrual bleeding patterns in pre- and perimenopausal women: a population-based prospective diary study
Karen Astrup1, Niels de Fine Olivarius, Susanne Møller
1Central Research Unit and Department of General Practice, University of Copenhagen, Copenhagen, Denmark. k.astrup@dadlnet.dk
Acta Obstetricia Et Gynecologica Scandinavica
|February 6, 2004
Summary
Menstrual cycle irregularity is common in pre- and perimenopausal women, leading to varied bleeding patterns. This includes increased spotting and prolonged bleeding episodes as women approach menopause.
Area of Science:
- Reproductive endocrinology
- Gynecology
- Population health
Background:
- Investigating natural menstrual bleeding patterns in pre- and perimenopausal women.
- Prospective observational population study design.
Purpose of the Study:
- To characterize menstrual bleeding patterns in pre- and perimenopausal women.
- To assess the relationship between cycle regularity and bleeding characteristics.
Main Methods:
- Population-based sample of 2000 Danish women aged 45-54 years.
- 1616 women completed an initial questionnaire; 951 with natural cycles recorded daily bleeding for 1 year.
- 592 pre- or perimenopausal women were included in the final analysis.
Main Results:
- Cycle irregularity increased from 58.3% at ages 45-46 to 100% at ages 53-54.
- Irregular cycles correlated with increased variation in bleeding length and heaviness.
- Spotting and prolonged bleeding (≥10 days) were more frequent with irregular cycles, while heavier bleeding was reported with regular cycles.
Conclusions:
- Menstrual cycle irregularity is prevalent at the end of the reproductive period.
- Irregular cycles are associated with greater variability in bleeding episode length and heaviness.
- Increased frequency of prolonged bleeding and spotting are key features of irregular cycles in this age group.