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Related Experiment Videos

Successful adherence after multiple HIV treatment failures.

Maithe Enriquez1, Nancy R Lackey, Mary C O'Connor

  • 1School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. maithe_enriquez@unc.edu

Journal of Advanced Nursing
|February 6, 2004
PubMed
Summary

Understanding readiness for HIV medication adherence is key. This study found that a trigger event and supportive factors help previously non-adherent patients achieve successful treatment outcomes.

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Area of Science:

  • Medical Science
  • Psychology
  • Public Health

Background:

  • Non-adherence to human immunodeficiency virus (HIV) medications leads to drug resistance and poor health outcomes.
  • Care providers often delay HIV treatment until patients are perceived as 'ready' for adherence.
  • Limited research exists on the process of developing readiness for successful HIV medication adherence.

Purpose of the Study:

  • To describe and understand the experiences and decision-making processes of individuals who achieved adherence to HIV medication after prior non-adherence.
  • To explore the phenomenon of 'readiness' in the context of HIV treatment adherence.

Main Methods:

  • Phenomenological study utilizing a Husserlian approach.
  • In-depth interviews analyzed using Giorgi's method of phenomenological description and analysis.

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  • Purposeful selection of 13 HIV-positive participants with a history of non-adherence.

    • Main Results:

    • Participants experienced a 'trigger' event that initiated the adherence process.
    • Key factors for sustained adherence included changing medication attitudes, finding supportive providers, building a support system, gaining life control, and setting goals.
    • Sustained adherence was achieved for at least 1 year without formal intervention.

    Conclusions:

    • Readiness is a crucial component for successful HIV treatment adherence, especially for those with a history of non-adherence.
    • Findings inform clinical decision-making for managing 'difficult-to-treat' patients.
    • Understanding readiness can guide interventions to improve adherence and prevent HIV drug resistance.