Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Consensus guidelines on anti-cardiolipin antibody testing and reporting.

Richard C W Wong1, David Gillis, Stephen Adelstein

  • 1Division of Immunology, Queensland Health Pathology Services, Princess Alexandra and Royal Brisbane Hospitals, Qld., Australia. richard_wong@health.qld.gov.au

Pathology
|February 6, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute and longitudinal magnetic resonance imaging abnormalities in antibody-mediated encephalitis.

Brain communications·2026
Same author

Plasma proteome in LGI-1 autoimmune encephalitis.

Journal of neuroinflammation·2026
Same author

Reflex lymphocyte subset enumeration for infants with lymphopenia as a surrogate screening tool for severe combined immunodeficiency: a single-centre experience.

Pathology·2026
Same author

Clinical Images: Co-occurrence of Bywaters lesions and Jaccoud arthropathy in a patient.

ACR open rheumatology·2026
Same author

Flow cytometric assessment of measurable residual disease in acute myeloid leukaemia: a summary of current Australasian practice and future directions.

Internal medicine journal·2026
Same author

Biomarkers of neuroaxonal and astrocytic pathology in autoimmune encephalitis.

Brain, behavior, and immunity·2025

Consensus guidelines for anti-cardiolipin antibody (aCL) testing standardize laboratory practices. These recommendations aim to reduce variation in aCL assay performance and reporting for improved diagnostic accuracy.

Area of Science:

  • Clinical Immunology
  • Laboratory Medicine

Background:

  • Anti-cardiolipin antibodies (aCL) are crucial biomarkers for anti-phospholipid antibody syndrome (APS).
  • Laboratory variation in aCL testing can impact diagnostic accuracy and patient management.

Framework:

  • Development of consensus guidelines to standardize aCL testing and reporting.
  • Recommendations cover assay performance, specimen handling, controls, calibrators, and result interpretation.

Implementation:

  • Guidelines address specific aspects including isotype testing, specimen type, assay precision, and cut-off values.
  • Inclusion of recommendations for rheumatoid factor and IgM aCL testing.
  • Emphasis on standardized reporting and interpretative comments.

Implications:

Related Experiment Videos

  • Minimizing laboratory variation in aCL testing.
  • Enhancing the reliability and consistency of aCL assay results.
  • Improving the diagnosis and management of conditions associated with aCL.