Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphogens, their identification and regulation.

Tetsuya Tabata1, Yuki Takei

  • 1Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-0032, Japan. ttabata@ims.u-tokyo.ac.jp

Development (Cambridge, England)
|February 6, 2004
PubMed
Summary

Morphogens are signaling molecules that guide cell differentiation during development. Understanding their concentration gradients is key to deciphering developmental patterns and cell fate determination.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electronic symptom monitoring improves chemotherapy dose intensity in neoadjuvant chemotherapy for breast cancer.

Current problems in cancer·2025
Same author

Early detection of drug-induced interstitial lung disease using an electronic patient-reported outcome system: a report of two cases.

International cancer conference journal·2025
Same author

Preclinical Prediction of Resistance Mutations and Proposal of Sequential Treatment Strategies for ALK-positive Lung Cancer Using Next-generation ALK Inhibitors.

Pharmaceutical research·2025
Same author

Extremely stripped supernova reveals a silicon and sulfur formation site.

Nature·2025
Same author

Direct measurement of absolute radiation pressure of leds in nanopascal range under ambient conditions with microcantilever.

Scientific reports·2025
Same author

Domain structure and function of α-1,3-glucanase Agl-EK14 from the gram-negative bacterium Flavobacterium sp. EK-14.

Journal of bioscience and bioengineering·2024

Area of Science:

  • Developmental Biology
  • Cell Signaling
  • Genetics

Background:

  • Cell differentiation relies on positional information.
  • Morphogens establish concentration gradients to signal cells.
  • These gradients prefigure developmental patterns.

Purpose of the Study:

  • To describe the identification and analysis of morphogens.
  • To explain the functions of morphogens in development.
  • To focus on extensively studied model systems.

Main Methods:

  • Analysis of morphogen signaling pathways.
  • Study of concentration gradient formation.
  • Investigation using established developmental model systems.

Main Results:

  • Identification of key signaling molecules (morphogens).
  • Characterization of morphogen gradient formation and function.
  • Elucidation of how gradients dictate cell fate.

Conclusions:

  • Morphogen gradients are crucial for pattern formation.
  • Understanding morphogen mechanisms provides insight into development.
  • Model systems are vital for studying these complex processes.

Related Experiment Videos