Related Experiment Video
Updated: Aug 2, 2026

Spinal Cord Transection in the Larval Zebrafish
Published on: May 21, 2014
Spinal cord regeneration: moving tentatively towards new perspectives
D G Jones1, E R Anderson, K A Galvin
1Department of Anatomy and Structural Biology, University of Otago, Dunedin, New Zealand. gareth.jones@stonebow.otago.ac.nz
Abstract:
The failure of the adult human spinal cord to regenerate following injury is not absolute, but appears to be amenable to therapeutic manipulation. Recent work has shown that the provision of a growth permissive environment by the neutralization of inhibitory influences, or the grafting of fetal tissue, peripheral nerve, Schwann cells, or olfactory ensheathing cells can enhance regeneration in animal models of spinal cord injury. Stem cells are gaining ever-increasing favour as a treatment option for spinal cord injury. The potential of neural stem cells, embryonic stem cells, and bone marrow stromal cells is discussed. Additional treatment options such as pharmacological interventions, functional electrical stimulation and physiotherapy approaches are also explored. Basic science insights are used as a foundation for a discussion of a variety of clinical perspectives including repair of the chronically injured spinal cord, animal models of human spinal cord injuries and clinical trials. A more holistic approach towards spinal cord injury is suggested, one where a hierarchy of needs is recognised and quality of life is paramount. Finally, this review cautions against overly grandiose claims of an imminent miracle cure for human spinal cord injury.
More Related Videos
Related Concept Videos
The Spinal Cord
Whole Body Regeneration
Neurogenesis and Regeneration of Nervous Tissue
Spinal Cord: Gross Anatomy
Spinal Cord: Information Processing
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Spinal Cord

