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Published on: January 29, 2018
Variable presentations of rickets in children in the emergency department
Erete Bloom1, Eileen J Klein, Denise Shushan
1Department of Pediatrics, University of Washington and Children's Hospital and Regional Medical Center, Seattle, WA.
Insights
Vitamin D-deficient rickets, though uncommon, is increasing in children, often presenting with fractures or seizures. Prompt diagnosis and treatment of nutritional rickets are crucial for symptom resolution.
Area of Science:
- Pediatrics
- Nutritional Science
- Endocrinology
Background:
- Nutritional rickets due to vitamin D deficiency is increasingly recognized in pediatric populations.
- The rise may be linked to increased rates of breastfeeding, which can be low in vitamin D.
- Rickets should be considered in various clinical scenarios presenting with specific symptoms.
Observation:
- Three pediatric cases of rickets presenting to the emergency department are detailed.
- Presentations included fractures (initially concerning for abuse), tetany, and hypocalcemic seizures.
- These acute symptoms were directly related to underlying rickets.
Findings:
- Laboratory and radiographic evaluations confirmed nutritional rickets in all presented cases.
- Symptoms, including fractures and seizures, resolved effectively with appropriate vitamin D treatment.
- The clinical presentations highlighted the diverse and sometimes severe manifestations of vitamin D deficiency.
Implications:
- Clinicians should maintain a high index of suspicion for vitamin D-deficient rickets in children with concerning presentations.
- Early recognition and management are vital to prevent severe complications and ensure recovery.
- Public health awareness regarding vitamin D sources and supplementation may be warranted.
Abstract:
Vitamin D-deficient rickets is uncommon but becoming more prevalent in the pediatric population likely related to increases in breast-feeding. It should be considered in many clinical situations. We present 3 cases of rickets presenting acutely to the emergency department. Their presentations included a fracture concerning for child abuse, tetany, and hypocalcemic seizures. In all cases, laboratory and radiographic evaluations were consistent with the diagnosis of nutritional rickets and their symptoms were related to rickets resolved with appropriate treatment. Although uncommon, vitamin D-deficient rickets should be considered in children with the above presentations.
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