Related Experiment Video
Updated: Aug 29, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
Silicone rubber: an alternative for repair of articular cartilage defects
1Institute of Sports Medicine, Third Hospital, Peking University, No. 49, North Garden Road, Haidian District, 100083, Beijing, P.R. China. yuchangl@public3.bta.net.cn
Abstract:
Silicone-rubber implants were used to fill full-thickness articular cartilage in the trochlea area of the knee joint in rabbits, for the purpose of studying the long-term influence of silicone-rubber implant on surrounding articular cartilage. Forty eight weeks after surgery, the silicone rubbers were still fitted tightly into the defects; surrounding cartilage showed mild degeneration, better than the control group. Our results showed silicone-rubber implantation for repairing local articular cartilage defects can effectively delay the pathogenetic progression of osteoarthritis.

