Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Versatile and open software for comparing large genomes.

Stefan Kurtz1, Adam Phillippy, Arthur L Delcher

  • 1Center for Bioinformatics, University of Hamburg, Bundesstrasse 43, 20146 Hamburg, Germany.

Genome Biology
|February 5, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Testing the reliability of AI-generated protein structures.

bioRxiv : the preprint server for biology·2026
Same author

BiTUGA: scalable prevalence-based unitig association testing for binary traits.

G3 (Bethesda, Md.)·2026
Same author

A complete human pancreatic cancer genome.

bioRxiv : the preprint server for biology·2026
Same author

Comparison of unbiased metagenomic next generation sequencing to targeted multiplex diagnostic assays for the detection of respiratory viruses.

PloS one·2026
Same author

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling.

eLife·2026
Same author

A reference genome sequence for the exceptionally long-lived Great Basin bristlecone pine, Pinus longaeva.

G3 (Bethesda, Md.)·2026
Same journal

Integrated lipidomic and transcriptomic profiling of the host response in human malaria.

Genome biology·2026
Same journal

Centromeric satellite expansion drives genome evolution in the snowy owl.

Genome biology·2026
Same journal

Mapping the landscape of allele-specific expression in porcine genomes.

Genome biology·2026
Same journal

Genomic sequence evolution underlying human neocortical interareal diversification.

Genome biology·2026
Same journal

Regulatory mechanisms driven by functional 3'-UTR variants in alcohol use disorder and related traits.

Genome biology·2026
Same journal

A longitudinal single-nucleus transcriptomic atlas of bovine placentation reveals dynamic cellular hierarchies and regulatory programs.

Genome biology·2026
See all related articles

The latest MUMmer software efficiently compares large eukaryotic genomes, even those distantly related. This open-source tool includes new graphical viewers for analyzing genome alignments.

Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • Genome comparison is crucial for understanding evolutionary relationships and genomic structures.
  • Existing tools may face limitations when analyzing large eukaryotic genomes or those with significant evolutionary divergence.

Purpose of the Study:

  • To introduce the newest version of MUMmer, highlighting its enhanced capabilities for large-scale eukaryotic genome comparisons.
  • To present novel graphical viewing tools for improved analysis of genome alignments.
  • To announce the open-source release of MUMmer, fostering community contribution and accessibility.

Main Methods:

  • Utilized the newest version of the MUMmer software system.
  • Applied MUMmer to perform comparisons across multiple eukaryotic genomes with varying evolutionary distances.

Related Experiment Videos

  • Employed two newly developed graphical viewing tools for data analysis.

    • Main Results:

    • The latest MUMmer version effectively handles comparisons of large eukaryotic genomes across diverse evolutionary distances.
    • New graphical tools offer alternative and potentially more intuitive methods for analyzing genome alignment data.
    • The software is now available as open-source, enabling broader access and collaborative development.

    Conclusions:

    • The updated MUMmer system provides a robust and accessible platform for large-scale eukaryotic genome comparison.
    • The open-source nature of MUMmer is expected to accelerate advancements through community involvement.
    • Graphical viewing tools enhance the interpretability of complex genome alignment data.