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Ferric Chloride-induced Murine Thrombosis Models
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Published on: September 5, 2016

[Changes in the thrombocyte and procoagulant links in hemostasis in patients with arterial hypertension]

A M Vasilenko, V N Kovalenko, A P Kuz'mina

    Likars'Ka Sprava
    |August 1, 1992
    PubMed

    A study of 62 workers with arterial hypertension of the ore mining industry revealed significant and various changes of the thrombocytic and coagulation hemostasis in patients. Hyperfibrinemia, increase of adhesive-aggregation properties of cellular elements, depression of fibrinolysis creates a thrombogenic situation. For choice of treatment tactics in clinical conditions it is recommended to evaluate the thrombocytic and procoagulant links of hemostasis. Disorders in the system of primary hemostasis (increase of adhesive-aggregational properties of cellular elements) are an indication to the use of antiaggregants (tyclid, tyclopidin). In case of fibrinolysis depression, anticoagulants should be used in the therapy complex.

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