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The immunopathogenic role of food hypersensitivity in atopic dermatitis
1Division of Allergy/Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Acta Dermato-Venereologica. Supplementum
|January 1, 1992
Abstract:
Food hypersensitivity is reported to play an immunopathogenic role in atopic dermatitis in approximately one-third of children. In 320 selected children with moderate to severe atopic dermatitis, 63% of children were found to have food hypersensitivity by double-blind placebo-controlled food challenges. Both IgE-mediated mast cell and mononuclear cell activation appear responsible for the eczematous lesions resulting from ingestion of food allergens.