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Updated: Aug 29, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Clinical characteristics of obstructive sleep apnea syndrome in children]
Da-bo Liu1, Jian-wen Zhong, Shao-peng Luo
1Department of Otorhinolaryngology, Guangzhou Children's Hospital, Guangzhou 510120, China.
Insights
Adenotonsillar hypertrophy is a key cause of obstructive sleep apnea syndrome (OSAS) in children, characterized by snoring and apnea. Polysomnography (PSG) is crucial for diagnosis, and surgery significantly improves patient outcomes.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Otolaryngology
Context:
- Obstructive sleep apnea syndrome (OSAS) in children is a growing concern.
- Adenotonsillar hypertrophy is frequently implicated as a primary cause.
- Accurate diagnosis and effective treatment are essential for pediatric patient health.
Purpose:
- To investigate the clinical features and diagnostic methods for OSAS in children.
- To evaluate the efficacy of tonsillectomy and adenoidectomy in treating pediatric OSAS.
- To establish polysomnography (PSG) as a definitive diagnostic tool.
Summary:
- This study reviewed 60 children diagnosed with OSAS, analyzing polysomnography (PSG) parameters including apnea-hypopnea index (AHI) and oxygen saturation.
- Adenotonsillar hypertrophy and loud snoring were present in all participants.
- Surgical intervention (tonsillectomy and adenoidectomy) in 40 children led to statistically significant improvements in all measured PSG parameters (P < 0.01), with a clinical efficacy rate exceeding 90%.
Impact:
- Highlights adenotonsillar hypertrophy as a major contributor to pediatric OSAS.
- Emphasizes the diagnostic significance of snoring, dyspnea, apnea, and hypoventilation.
- Reinforces the necessity of PSG for confirming OSAS diagnosis in children.
- Demonstrates the high effectiveness of surgical treatment for OSAS caused by adenotonsillar hypertrophy.
Objective:
To explore the clinical features and diagnosis of obstructive sleep apnea syndrome (OSAS) in children.
Methods:
Sixty children with OSAS were reviewed, every patient was monitored with polysomnography (PSG) for 7 hours at night for 11 parameters, including the longest apnea time (LAT), apnea and hypopnea index (AHI), the lowest oxygen saturation (SaO(2)), and snore index etc., the parameters of the 2 groups were compared. Meanwhile, tonsillectomy and adenoidectomy were performed for 40 cases of OSAS, and the parameters obtained before and after operation were analyzed.
Results:
Adenotonsillar hypertrophy and the loud snoring during sleep were found in all cases. The mean values of the PSG parameters were as follows: the longest apnea time was 53 (8-178) seconds (s); the total time of apnea was 310.5 (26-5,260) s; the time of apnea was 26 (3-240) s; the longest hypopnea time was 41 (5-94) s; the total times of hypopnea was 170 (5-2,860) s; the time of hypopnea was 10 (1-85); the apnea index was 4.1 (0.5-25.9); the hypopnea index was 1.4 (0-16.1); the apnea and hypopnea index (AHI) was 6.8 (0.5-38.2); the snore index was 81.7 (1.3-414.8); the lowest saturation of oxygen was 0.78 (0.25-0.93). There was not statistically significant difference in the parameters between 2-7 year group and over 7 year group (P > 0.05). The parameters of postoperation group: the mean value of the longest apnea time was 15.5 (0-60) s; the total time of apnea was 56.4 (60-205) s; the time of apnea was 10.33 (0-40); the longest hypopnea time was 13.25 (0-30) s; the total times of hypopnea was 44.6 (0-73); the hypopnea time was 4.32 (0 - 30) s; the apnea index was 0.6 (0-12); the hypopnea index was 0.62 (0-4); the apnea and hypopnea index (AHI) was 1.25 (0.1-12); the snore index was 30.08 (1.8-102); the lowest oxygen saturation was 93.5% (64%-97%). Compared with preoperation groups there was a statistically significant difference (P < 0.01). Clinically effective rate of the surgeries was over 90%.
Conclusion:
Adenotonsillar hypertrophy seemed to be an important cause of OSAS in children. Snoring, dyspnea, apnea and low ventilation are the major clinical characteristics of OSAS in children. Confirmed diagnosis of the syndrome in children requires PSG recordings.
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