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Updated: Aug 29, 2026
A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
[Epidemiological study of gem worker's silicosis]
Dong-hui Zhang1, Chuang-yi Qiu, Huan-ying Li
1Guangdong Prevention & Treatment Center for Occupational Disease, Guangzhou 510300, China.
Objective:
To study the hazards of gem dusts and the epidemiological features of the occurrence of gem worker's silicosis (GWS).
Methods:
Epidemiological investigation in a gem factory in Guangdong province was carried out.
Results:
The average dusts concentration in workshop was 2.3 mg/m(3), average free silica content was 94.64%. There were 47 patients diagnosed as silicosis. The prevalence of GWS was 4.58% (47/ 1,027). The age of patients suffering from silicosis and the duration of dust exposure were (27.04 +/- 3.25) years and (4.67 +/- 1.17) years respectively. Chest radiographic examination showed mainly small round opacities "q". The incidences of GWS complicated by pulmonary tuberculosis, spontaneous pneumothorax and pulmonary emphysema were 10.64%, 10.64%, 44.68% respectively.
Conclusion:
The hazards of gem dust to workers might be serious. Higher incidence, younger age suffered from silicosis, shorter duration of dust exposure, more complications, and poorer prognosis in gem workers appeared to be the main epidemiological features of GWS in Guangdong.
