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Updated: Aug 29, 2026

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
[Clinical observation of the effect of tangential excision within 24 postburn hours on the patients with deep partial
Shu-liang Lu1, Zhen-jiang Liao, Jun Xiang
1Burn Institute of Shanghai, Ruijin Hospital, Shanghai Second Medical University, Shanghai, 200025, P.R. China.
Objective:
To investigate the safety and the clinical effect of the tangential excision of the patients with deep partial thickness burn within 24 postburn hours (PBHs).
Methods:
Twelve patients with deep partial thickness burn with the indication for tangential excision, the operation was carried out within 24 PBHs. These patients were designated as group A. Another group of fourteen patients with similar conditions undergoing tangential excision during 4 - 6 PBDs were designated as group B. The amount of fluid infusion during shock stage, the shock signs, the vital signs during recovery period, the urine output, as well as the healing time were compared between the two groups.
Results:
There was no obvious difference in the amount of fluid infusion and the shock signs between the two groups. There were evident differences in the body temperature and heart rate during recovery period, with the urine output increased dramatically during shock stage in group A when compared with those in group B (P < 0.05-0.01). The average wound healing days in group A were less than that in group B (P < 0.01).
Conclusion:
Tangential excision within 24 PBHs was applicable and safe for the patients with deep partial thickness burn, and wound healing time was thus shortened.
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