Trend of IgD values during the hyposensitization in children suffering from bronchial asthma

In 50 children, aged from 3 to 14 years, with bronchial asthma the IgD values were determined before and during the hyposensitization. The estimation of IgD values was made with method of single radial immunodiffusion, using Partigen plates - Behringwerke products. The IgD values were determined in seven serum samples in each investigated child. In 7 cases (14%) IgD was not found before hyposensitization. From 43 cases (86%) in whom the IgD value was found 34 (79%) had IgD values under 50% from the standard value and only 9 cases (21%) had the values over 50%. During the hyposenitization it came to changes in distribution of IgD values and only in 11 cases (29%) it came to real increase of IgD values. All investigated children had positive "skin-sensitive" reaction during the hyposensitization. On the base of the results obtained it could not be drawn a conclusion on relation between the IgD values and the effect of hyposensitization.