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Updated: Aug 29, 2026

Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head
Published on: January 3, 2020
[Pancreatic insulinomas: diagnosis and treatment]
Franz Robert Apodaca-Torrez1, Tarcisio Triviño, Edson José Lobo
1Disciplina de Grastroenterologia Cirúrgica do Departamento de Cirurgia da Universitade Federal de São Paulo - Escola Paulista de Medicina, São Paulo, Brasil. apodaca@uol.com.br
Background:
Despite its rarity, the insulinoma is the most common pancreatic neuroendocrine tumor.
Objective:
Analyze clinical and immunohistochemical data from surgical resection of the pancreas insulinoma.
Method:
Twelve cases are described, concerning surgical aspects, complications and medium-long term outcome of patients. They underwent surgical treatment due to clinical suspicion and biochemical diagnosis of hypoglycemia and hyperinsulinism.
Results:
The insulinoma was identified preoperatively in seven patients, while intraoperative ultrasonography and palpation were necessary for diagnosis in the other cases. Eight patients underwent pancreatic resection and pancreatic leak was observed in seven cases. Two patients developed diabetes mellitus and no mortality occurred in the current series.
Conclusion:
All patients presented satisfactory outcome and remained asymptomatic with normal glicemia levels.
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