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[Chronic subdural hematoma: study of 161 patients and the relationship with coagulation abnormalities]

Clarissa Lin Yasuda1, Márcia Elisabete Morita, Fernanda Yoshi Nishimori

  • 1Faculdade de Ciência Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.

Arquivos De Neuro-Psiquiatria
|February 6, 2004
PubMed

Insights

Pre-operative coagulation analysis is crucial for chronic subdural hematoma surgery outcomes. Abnormal INR or thrombocytopenia significantly increases mortality risk in these patients.

Area of Science:

  • Neurosurgery
  • Hematology

Context:

  • Chronic subdural hematoma (CSH) is a common intracranial hemorrhage.
  • Retrospective analysis of 161 CSH patients operated between 1994-2000 at UNICAMP.

Purpose:

  • Characterize the CSH patient population.
  • Evaluate the impact of pre-operative coagulation status on surgical outcomes.

Summary:

  • The majority of patients were male (86%), white (85.1%), with a median age of 57 years.
  • Elevated INR (>1.25) and/or thrombocytopenia were associated with significantly higher postoperative mortality (p<0.001, p=0.004).
  • A history of head injury correlated with lower mortality (p=0.044).

Impact:

  • Highlights the critical role of pre-operative coagulation screening in CSH management.
  • Suggests correcting coagulation abnormalities pre-surgery to improve patient outcomes.
  • Informs surgical planning and risk stratification for intracranial hemorrhage patients.

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