Marie Stopes Society, Pakistan: 1000 cases of quinacrine sterilization (QS)
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Published on: October 11, 2019
1Marie Stopes Society, Karachi, Pakistan.
Objectives:
To evaluate the safety, efficacy and acceptability of QS in Karachi, Pakistan.
Methods:
1000 women who had chosen sterilization during the 4-year period 1994 to 1997 inclusive were offered QS at both stationary clinics and in a mobile van at 23 sites in the outskirts of Karachi. The protocol involved transcervical insertion to the uterine fundus of 252 mg quinacrine in 7 pellets and 55 mg of ibuprofen in 3 pellets through an IUD inserter, during the proliferative phase of the menstrual cycle. Two doses were administered one month apart. A temporary method of contraception was provided for 3 cycles, usually DMPA. Follow-up was scheduled: monthly for 3 months, quarterly for 1 year and then every 6 months for 4 years.
Results:
The crude pregnancy rate after 4 years was 2.0%. Minor complications and complaints were reported by 59% of the patients. There was one ectopic pregnancy and no major complications.
Conclusions:
QS was found to be safe and effective and has become the most popular method of sterilization in our area of Pakistan.
