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Quinacrine sterilization (QS) in Costa Rica: 694 cases
1Department of Obstetrics and Gynecology, Hospital San Rafael, Alajuela, Costa Rica. falpizar@bytecr.com
Objectives:
To evaluate the safety, efficacy and acceptability of quinacrine sterilization (QS) in Costa Rica.
Methods:
From 1989 though August 1993, 694 women volunteered for QS in my private practice. All were referred by a family planning clinic or a local hospital obstetric service. The protocol used involved the transcervical insertion of 216 mg of quinacrine hydrochloride in the form of 6 pellets. A second dose was given 4 weeks later. All insertions were done in the first 14 days of the menstrual cycle. The procedure was similar to the CuT IUD placement. Temporary contraception was recommended for 3 months after the last insertion. The cut-off date for this analysis was April 1994.
Results:
With 7 months to 5 years of follow-up, the gross pregnancy rate was 2.5%. Side effects were relatively minor, none requiring hospitalization.
Conclusion:
QS was found to be safe, effective and acceptable.
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