Related Experiment Video
Updated: Aug 29, 2026

Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
[Pelvic inflammatory disease associated with Neisseria meningitis bacteremia]
Alberto F Leoni1, Ana Littvik, Susana B Moreno
1Servicio de Infectología, Hospital Guillermo Rawson, Bajada Pucará 2025, 5014 Córdoba. leoniasia@topmail.com.ar
Abstract:
The Pelvic Inflammatory disease (PID) caused by Neisseria meningitidis (Nm), as an extraneurological manifestation considered as a case study with few precedents. It is so far known that the occasional transposition of ecological niches occurs. There are several bibliographical reports that show an increase in the colonization of the genitourinary tract due to Nm. These may or may not cause disease in individuals during colonization. In adults, the symptoms and any complications which may arise are similar to those caused by Neisseria gonorrhoeae (Ng). It is highly necessary to correctly identify the agents of Neisseria gender which are obtained from the genital tract. This permits an accurate diagnosis to be made and results in a better understanding of the epidemiology. Morbimortality arising from Nm infection is worth studying to produce a better knowledge of the pathogenia of the infection caused by this microorganism.
Insights
Pelvic Inflammatory Disease (PID) can be caused by Neisseria meningitidis (Nm), a rare extraneurological manifestation. Accurate identification of Neisseria species in genital samples is crucial for diagnosis and understanding PID epidemiology.
Area of Science:
- Microbiology
- Infectious Diseases
- Gynecology
Background:
- Neisseria meningitidis (Nm) is primarily known for causing meningitis.
- Recent reports indicate an increasing colonization of the genitourinary tract by Nm.
Observation:
- Pelvic Inflammatory Disease (PID) is rarely caused by Nm, presenting as an extraneurological manifestation.
- Symptoms and complications of Nm-induced PID resemble those caused by Neisseria gonorrhoeae (Ng).
Findings:
- This case study highlights the potential for Nm to cause PID.
- Distinguishing Nm from Ng in genital samples is critical for accurate diagnosis.
Implications:
- Improved identification of Neisseria species in genital tracts enhances diagnostic accuracy.
- Further research into Nm pathogenia is needed to understand PID epidemiology and reduce morbidity/mortality.
Related Concept Videos
Bacterial Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Viral Meningitis
Acute Pyelonephritis I: Introduction
Atypical Pneumonia

