Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exploring genome architecture through GOV: a WWW-based gene order visualizer.

Kishore R Sakharkar1, Vincent T K Chow

  • 1BioInformatics Institute, Biopolis street, Singapore 138671. kishore@bii.a-star.edu.sg

Bioinformatics (Oxford, England)
|February 7, 2004
PubMed
Summary

A new web-based tool visualizes and compares gene order across prokaryotic and viral genomes. This computational tool aids in analyzing large genomic datasets, revealing gene function and orthologs through sequence extraction and BLAST analysis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combination of Remdesivir and Ivermectin Exerts Highly Potent and Synergistic Antiviral Activity Against Murine Coronavirus and SARS-CoV-2 Infections.

Cells·2026
Same author

Differential Induction and Signaling of Type I and III Interferons During Infection of Human Nasal Epithelial Cells With the Four Human Parainfluenza Virus Types.

Journal of medical virology·2026
Same author

Combinations of Favipiravir with Doxycycline, Azithromycin or Ivermectin Exert Synergistic Effects Against Influenza A H3N2 Virus Replication.

Pathogens (Basel, Switzerland)·2026
Same author

Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue.

Viruses·2025
Same author

Enterovirus-A71 exploits RAB11 to recruit chaperones for virus morphogenesis.

Journal of biomedical science·2024
Same author

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

Viruses·2024

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Advancements in sequence analysis now allow simultaneous examination of multiple genes and proteins.
  • The analysis of large-scale genomic datasets requires effective, user-friendly software tools.
  • Integration with public domain software is crucial for broader accessibility.

Purpose of the Study:

  • To describe a web-based interactive computational tool for genome-level data mining.
  • To enable visualization and comparison of gene order across multiple genomes.
  • To facilitate functional analysis of genes and identification of orthologs.

Main Methods:

  • Development of a web-based interactive computational tool.
  • Implementation of visualization and comparison features for gene order.

Related Experiment Videos

  • Integration of nucleotide sequence extraction and BLAST analysis capabilities.
  • Main Results:

    • The tool enables effective visualization and comparison of gene order in prokaryotic and viral genomes.
    • Intriguing similarities and differences in gene order across multiple genomes are revealed.
    • Users can easily extract gene sequences for functional insights and ortholog identification via BLAST analysis.

    Conclusions:

    • The developed tool addresses the need for user-friendly, genome-level data mining.
    • It provides valuable insights into comparative genomics and gene function.
    • The tool enhances the accessibility of complex genomic data analysis for a wider scientific community.