Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetic amniocentesis in multiple pregnancy.

Erno Tóth-Pál1, Csaba Papp, Artúr Beke

  • 11st Department of Obstetrics and Gynecology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

Fetal Diagnosis and Therapy
|February 7, 2004
PubMed
Summary

Genetic amniocentesis in multiple pregnancies showed a slight increase in fetal loss before 24 weeks. However, the procedure did not impact perinatal mortality rates in this study.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum for Bende et al., "The <i>Neosartorya (Aspergillus) fischeri</i> antifungal protein NFAP2 has low potential to trigger resistance development in <i>Candida albicans in vitro</i>".

Microbiology spectrum·2026
Same author

Micafungin microevolution in <i>Candida auris</i> reveals resistance development without <i>in vivo</i> fitness compromise.

Virulence·2026
Same author

Screening the γ-core Motif Peptides of Ascomycetous Antifungal Proteins for Antifungal Activity and Potential Therapeutic Applicability.

Probiotics and antimicrobial proteins·2026
Same author

Effects of a 6-Month Exercise Intervention on Primitive Reflexes in Children with Developmental Language Disorder-A Case for Multisensory and Sensorimotor Integration.

Children (Basel, Switzerland)·2025
Same author

Associations Between Fetal Symptoms During Pregnancy and Neonatal Clinical Complications with Cytomegalovirus Infection.

Children (Basel, Switzerland)·2025
Same author

Beyond plasma membrane disruption: Novel antifungal mechanism of Neosartorya (Aspergillus) fischeri antifungal protein 2 in Candida albicans.

International journal of biological macromolecules·2025

Area of Science:

  • Perinatology
  • Prenatal Diagnostics
  • Genetics

Background:

  • Second-trimester genetic amniocentesis is a common invasive prenatal diagnostic technique.
  • Previous studies have explored its impact on fetal loss in multiple pregnancies.

Purpose of the Study:

  • To analyze the experience with genetic amniocentesis in multiple pregnancies over a 10-year period.
  • To evaluate the effect of genetic amniocentesis on fetal loss and perinatal mortality in multiple gestations.

Main Methods:

  • Retrospective analysis of 184 multiple pregnancies undergoing genetic amniocentesis.
  • Outcome data collected for 175 cases (95.1%).
  • Comparison with a control group of 300 twin pregnancies without amniocentesis.

Related Experiment Videos

Main Results:

  • Spontaneous loss rate between 18-24 weeks was 2.39% in controls versus 3.87% after amniocentesis.
  • The fetal loss rate increased by 1.48% before the 24th week following genetic amniocentesis.
  • Perinatal mortality rates were similar: 10.03/1,000 with amniocentesis vs. 10.52/1,000 without.

Conclusions:

  • Genetic amniocentesis in multiple pregnancies is associated with a small increase in fetal loss before 24 weeks.
  • No significant increase in fetal loss is expected beyond 5 weeks post-procedure.
  • The intervention did not adversely affect perinatal mortality rates.