Related Experiment Video
Updated: Aug 29, 2026

Studying Protein Function and the Role of Altered Protein Expression by Antibody Interference and Three-dimensional Reconstructions
Published on: April 21, 2016
The molecular basis of intellectual disability: novel genes with naturally occurring mutations causing altered gene
1Department of Cytogenetics and Molecular Genetics, Women's and Children's Hospital, North Adelaide, South Australia 5006. jozef.gecz@adelaide.edu.au
Abstract:
This review on the genes implicated in mental retardation, and its X-chromosome linked forms, we presented at the symposium 'The Regulation of Gene Expression in the Brain' (January 23-26, 2003, Heron Island Australia). The main purpose of the review was to highlight the current knowledge of the spectrum of the genes causing mental retardation, provide an insight in to their function(s), where known, and to speculate about the evolutionary processes which shaped such an unexpected concentration of these genes on the human sex chromosome X. Such genes with naturally occurring mutations provide an invaluable opportunity for identifying the pathways essential for the normal function of the brain. Once identified, cellular and animal models can then be used for experimentation
Related Concept Videos
Intellectual Disability
Biological Influences on Intelligence
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Gene-Environment Interactions
