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Updated: Aug 29, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
16-(4-Isopropylbenzylidene)androst-4-ene-3,17-dione
S Thamotharan1, V Parthasarathi, S Dubey
1Department of Physics, Bharathidasan University, Tiruchirappalli 620 024, India.
Abstract:
In the title compound, C(29)H(36)O(2), the outer cyclohexene ring of the steroid nucleus has a conformation that lies about half-way between a half-chair and an envelope, while the central and outer cyclohexane rings of the steroid nucleus have slightly distorted chair conformations. The steroidal cyclopentane ring adopts a 13beta,14alpha-half-chair conformation. The benzylidene moiety has an E configuration with respect to the carbonyl group on the cyclopentane ring. The dihedral angle between the mean planes of the steroid nucleus and the benzylidene moiety is 35.54 (9) degrees. The packing of the molecules is assumed to be dictated mainly by weak intermolecular C-H.O interactions.
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