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[Pulmonary embolism--mortality risk].

J F Sequeira¹, P C Duarte, I M Madruga

¹Serviço Medicina, Hospital Santa Maria, Lisboa.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology

|September 1, 1992

Summary

This study analyzed 146 pulmonary embolism (PE) patients, identifying key clinical findings and risk factors. Researchers developed a mortality index using discriminant analysis to predict outcomes in PE patients.

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Area of Science:

Pulmonary Medicine
Cardiology
Clinical Diagnostics

Context:

Pulmonary embolism (PE) poses a significant diagnostic and prognostic challenge.
Retrospective analysis of 311 patients with clinical PE diagnosis over three years.
146 patients met inclusion criteria after exclusion based on clinical-laboratorial parameters.

Purpose:

To identify frequent clinical findings and comorbidities in PE patients.
To investigate laboratory and diagnostic test results associated with PE.
To develop a discriminant analysis-based mortality index for PE patients.

Summary:

Frequent findings included dyspnea (94%), abnormal cardiopulmonary observation (89%), and venous thromboembolism risk factors (74%).
Comorbidities comprised heart failure (64%), myocardial ischemia (32%), and cancer (13%).

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Elevated LDH (54%), severe hypoxemia (55%), and suggestive ECG findings (37%) were noted. Right heart dysfunction occurred in 30% of cases.

Mortality was 25% (37 patients), with 54% of deaths occurring within 4 days of admission.

Discriminant analysis identified 14 items with good discriminative power for mortality prediction.

Impact:

The study provides insights into the clinical presentation and outcomes of PE.
Identified factors can aid in risk stratification and clinical decision-making.
The developed mortality index offers a tool for predicting PE patient outcomes.