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[Pulmonary embolism--mortality risk].

J F Sequeira1, P C Duarte, I M Madruga

  • 1Serviço Medicina, Hospital Santa Maria, Lisboa.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|September 1, 1992
PubMed
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This study analyzed 146 pulmonary embolism (PE) patients, identifying key clinical findings and risk factors. Researchers developed a mortality index using discriminant analysis to predict outcomes in PE patients.

Area of Science:

  • Pulmonary Medicine
  • Cardiology
  • Clinical Diagnostics

Context:

  • Pulmonary embolism (PE) poses a significant diagnostic and prognostic challenge.
  • Retrospective analysis of 311 patients with clinical PE diagnosis over three years.
  • 146 patients met inclusion criteria after exclusion based on clinical-laboratorial parameters.

Purpose:

  • To identify frequent clinical findings and comorbidities in PE patients.
  • To investigate laboratory and diagnostic test results associated with PE.
  • To develop a discriminant analysis-based mortality index for PE patients.

Summary:

  • Frequent findings included dyspnea (94%), abnormal cardiopulmonary observation (89%), and venous thromboembolism risk factors (74%).
  • Comorbidities comprised heart failure (64%), myocardial ischemia (32%), and cancer (13%).

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  • Elevated LDH (54%), severe hypoxemia (55%), and suggestive ECG findings (37%) were noted. Right heart dysfunction occurred in 30% of cases.
  • Mortality was 25% (37 patients), with 54% of deaths occurring within 4 days of admission.
  • Discriminant analysis identified 14 items with good discriminative power for mortality prediction.

    • Impact:

    • The study provides insights into the clinical presentation and outcomes of PE.
    • Identified factors can aid in risk stratification and clinical decision-making.
    • The developed mortality index offers a tool for predicting PE patient outcomes.