Related Experiment Video

Updated: Aug 29, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

[The clinical analysis of endophthalmitis caused by minor ocular perforation]

Zhen-he Fu1, Li-ya Guo, Yue-zhong Zheng

  • 1Tianjin Eye Hospital, Tianjin 300040, China. yankeyy@263.net

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|February 11, 2004
PubMed
Abstract

Insights

Minor ocular perforations can lead to severe endophthalmitis, causing significant vision loss. Early recognition and evaluation of infection risk are crucial for preventing vision impairment after eye injuries.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Trauma Surgery

Context:

  • Minor ocular perforations are a significant cause of vision-threatening complications.
  • Endophthalmitis following such injuries can rapidly lead to irreversible vision loss.
  • Understanding the incidence and risk factors is crucial for effective management.

Purpose:

  • To determine the incidence and causes of endophthalmitis after minor ocular perforations.
  • To document the impact of these injuries on visual function.
  • To improve the prevention strategies for endophthalmitis.

Summary:

  • A retrospective study analyzed 153 cases of minor ocular perforations.
  • Key data included injury characteristics, infection onset, and microbiological results.
  • Visual outcomes and treatment responses were evaluated, with 91.5% experiencing vision less than 0.3 and 24.2% requiring enucleation.

Impact:

  • Minor eye injuries can progress to severe endophthalmitis within hours, leading to profound vision loss.
  • Prompt recognition and risk assessment for endophthalmitis are vital in the early post-injury phase.
  • This study underscores the importance of timely intervention to prevent vision impairment.

More Related Videos

Induction of Ocular Surface Inflammation and Collection of Involved Tissues06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...