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Updated: Aug 2, 2026

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
Published on: May 30, 2020
Eosinophil function in allergic inflammation: from bone marrow to tissue response
Darryl Adamko1, Paige Lacy, Redwan Moqbel
1Department of Medicine, 550A HMRC, University of Alberta, Edmonton, AB T6G 2S2, Canada. Redwan.Moqbel@ualberta.ca
Abstract:
The role of the eosinophil in the pathophysiology of allergy and asthma has been the focus of intense interest during the past two decades. Although the presence of eosinophils in humans with allergy and asthma is well established, the precise role of this cell in human and animal tissue response is still unclear. However, recent developments in research on many organ systems have provided novel insights into the possible underlying role of the eosinophil in both allergic and nonallergic inflammation. In this review, we examine the pathways associated with eosinophil recruitment and activation, and discuss these findings with reference to clinically defined categories.
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