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A longitudinal study of pelvic inflammatory disease
C M Stacey1, P E Munday, D Taylor-Robinson
1Jefferiss Wing, St Mary's Hospital, Paddington, London, UK.
British Journal of Obstetrics and Gynaecology
|December 1, 1992
Summary
Pelvic inflammatory disease (PID) is often caused by Chlamydia trachomatis and Neisseria gonorrhoeae, leading to long-term fertility issues and pelvic pain in women. Microbiological investigations are crucial for understanding PID
Area of Science:
- Gynecology
- Infectious Diseases
- Microbiology
Background:
- Pelvic inflammatory disease (PID) is a significant cause of reproductive morbidity in women.
- Understanding the causative agents and long-term consequences of PID is essential for effective management.
Purpose of the Study:
- To investigate the microbiology of PID.
- To determine the long-term prognosis of PID, including fertility and pelvic pain.
Main Methods:
- A prospective study involving 23 women with laparoscopically confirmed PID.
- Microbiological investigations were conducted at diagnosis and follow-up.
- Assessment of subsequent fertility and occurrence of pelvic pain.
Main Results:
- Chlamydia trachomatis and Neisseria gonorrhoeae were identified as key pathogens in PID.
- Microorganisms were detected more frequently in the cervix than in the endometrium or tubes.
- After 1-3 years, 33% of women experienced conception difficulties and 56% reported persistent pelvic pain.
Conclusions:
- While the exact infectious cause can be challenging to pinpoint, C. trachomatis and N. gonorrhoeae are strongly implicated in PID.
- Mycoplasma hominis may contribute to PID, either alone or in combination with other microorganisms.