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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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Published on: October 16, 2013

Enhancing effect of butorphanol on medetomidine-induced sedation in pigs

M Sakaguchi1, R Nishimura, N Sasaki

  • 1Department of Veterinary Surgery, Faculty of Agriculture, University of Tokyo, Japan.

The Journal of Veterinary Medical Science
|December 1, 1992
PubMed

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Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.