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Updated: Aug 2, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
[A correlative study on post-stroke depression and CT, physical, psychological and social parameters]
1Department of psychiatry, First Affiliated Hospital, Suzhou medical college.
Abstract:
58 acute hospitalized CVD patients were selected as study group. Each patient was administered a series of standardized quantitative measures. As a result, we found a significant difference between hemisphere (L: 55% vs R: 28% P < 0.05), and the difference was result from the highest incidence rate of PSD observed in the left anterior CVD subgroup. Meanwhile, those with left anterior lesion (cortical and subcortical) had the greater severity of depression than any other lesions. A strong negative correlation between the severity of depression and AP% was observed for left CVD group. The result of multiple stepwise regression analysis not only support the notions mentioned above but also shown up that a few factors other than location of the lesion had impact on the PSD. Finally, authors discussed the heterogenous causes of PSD and think probably biological etiology involved in the formation of PSD.

