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[Endomyocardial biopsy in childhood]
M G Gagliardi1, M Bevilacqua, F Parisi
1Dipartimento Medico-Chirurgico di Cardiologia Pediatrica, Ospedale Bambino Gesù, Roma.
Giornale Italiano Di Cardiologia
|August 1, 1992
Summary
Pediatric endomyocardial biopsy is a safe procedure for diagnosing acute myocarditis and heart transplant rejection. While limited in other pediatric heart conditions, it offers crucial diagnostic value in specific cases.
Area of Science:
- Pediatric Cardiology
- Cardiac Pathology
- Interventional Cardiology
Context:
- Endomyocardial biopsy experience in pediatric patients is limited.
- This study reviews 144 procedures in 84 children (33 days to 14 years) between 1986 and 1990.
- The bioptome was introduced directly without a long sheath.
Purpose:
- To evaluate the safety and utility of right ventricle endomyocardial biopsy in pediatric patients.
- To assess its diagnostic yield for various pediatric cardiac conditions.
Summary:
- The study included patients with dilated, hypertrophic, and restrictive cardiomyopathy, heart tumors, and ventricular arrhythmias.
- Acute myocarditis was diagnosed in 27% of eligible dilated cardiomyopathy cases.
- Moderate to severe rejection was diagnosed in 47 out of 65 heart transplant recipients.
- The procedure was safe, with transient atrioventricular block and one right ventricular perforation as complications.
Impact:
- Right ventricle endomyocardial biopsy is a safe diagnostic tool in pediatric cardiology.
- Its primary utility lies in diagnosing acute myocarditis and heart allograft rejection.
- Findings aid in guiding therapeutic decisions for pediatric cardiac transplant recipients and myocarditis patients.