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Updated: Aug 6, 2026

Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
Published on: May 6, 2020
[A case of extrinsic allergic alveolitis in a shoe factory worker]
Abstract:
The article describes one case of exogenic allergic alveolitis (EAA) developed in female engaged into shoe-making during 20 years and exposed to high concentrations of industrial multicomponent aerosols. Having pneumonia-like exacerbations, the disease demonstrated growing dyspnea and intercurrent pulmonary infiltrations. Such diagnoses as pneumonia, pulmonary tuberculosis, Loeffler syndrome, pulmonary sarcoidosis and EAA were discussed. The diagnosis of "shoe-maker's" EAA was based on the features of anamnesis, occupational life and manifestations confirmed by immunologic and morphologic data. Endobronchial lavage with hydrocortisone administration was proved to be effective. The importance of clinical and immunologic criteria, examination of ability to work in people suffering from EAA was stressed.
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