Related Experiment Videos
Cutaneous alterations in patients with chronic renal failure
M R Picó1, A Lugo-Somolinos, J L Sánchez
1Department of Dermatology, University of Puerto Rico School of Medicine, San Juan 00936-5067.
International Journal of Dermatology
|December 1, 1992
Summary
All patients with chronic renal failure (CRF) experience skin problems, with pigmentation changes being most common. The type of renal replacement therapy, such as hemodialysis or peritoneal dialysis, influences the specific dermatologic manifestations observed.
Area of Science:
- Nephrology
- Dermatology
- Internal Medicine
Background:
- Chronic renal failure (CRF) is associated with numerous systemic complications.
- Dermatologic manifestations are common in patients with CRF but require thorough investigation.
Purpose of the Study:
- To determine the prevalence of skin conditions in patients with CRF.
- To analyze how hemodialysis and peritoneal dialysis affect dermatologic issues.
Main Methods:
- A cohort of 102 patients with CRF undergoing renal replacement therapy was clinically examined.
- Cutaneous alterations were systematically documented and analyzed.
Main Results:
- All patients exhibited at least one skin lesion, with altered cutaneous pigmentation being the most frequent finding.
- Hyperpigmented macules on palms and soles were notably prevalent.
- Hemodialysis patients showed higher rates of half-and-half nails, pruritus, and palm/sole keratotic pits.
- Peritoneal dialysis patients had a higher incidence of infectious skin processes.
Conclusions:
- Every patient with CRF presents with some form of cutaneous alteration.
- The modality of renal replacement therapy (hemodialysis vs. peritoneal dialysis) appears to influence the type and incidence of these skin changes.