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Effects of resin swelling and substitution on solid phase synthesis
K C Pugh1, E J York, J M Stewart
1Department of Biochemistry, University of Colorado School of Medicine, Denver.
Abstract:
Resins sold by several companies were examined for swelling, uniformity of beads, and substitution in the case of resins sold with the first amino acid attached. Effects of resin swelling, uniformity, and substitution on the solid phase synthesis of long, structured and/or branched peptides were evaluated.