Related Experiment Video
Updated: Aug 14, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
The quantification of alcohol-caused morbidity and mortality in Australia: a critique
1Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115.
Abstract:
One of the more controversial conclusions of the Commonwealth Department of Community Services and Health's report on The quantification of drug caused morbidity and mortality in Australia 1988 is that alcohol "causes" about 5% of all deaths in Australia. Against the background of this conclusion, this paper reviews current concepts of what constitutes a causal relationship and how the existence of causation is diagnosed in a nonexperimental setting. The conclusion of the report appears to rest on the assumption that all differences in disease rates between users and non-users of alcohol (or other drugs) are causal in nature--an assumption which is tantamount to equating statistical association with causation. Moreover, the estimate of alcohol-caused deaths, derived from the summation of alcohol-caused deaths from a large number of medical conditions, is at considerable variance with an estimate of total alcohol-caused deaths computed directly from total death rates. The latter estimate actually indicates that alcohol prevents more deaths than it causes in the population as a whole, a conclusion that is compatible with the findings of several recent large cohort studies, from which it is in fact derived. The discrepancy between the two estimates casts doubt on the validity of the assumptions underlying the methodology that has been applied.
More Related Videos
05:12Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
08:37Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
Published on: November 15, 2024
Related Concept Videos
Hypothesis Test for Test of Independence
H0: The two variables (factors)...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Stress Prevention and Stress Management Techniques IV