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[Cysts of the choroid plexus: personal experience]
B Mimmo1, G F Boggio, M Mossetti
1Clinica Ostetrica Ginecologica - Cattedra A, Università degli Studi di Torino.
Minerva Ginecologica
|November 1, 1992
Summary
Fetal choroid plexus cysts detected via ultrasound may indicate chromosomal abnormalities like trisomy 21. Prenatal diagnosis is recommended due to increased risk compared to maternal age alone.
Area of Science:
- Prenatal diagnosis
- Fetal medicine
- Medical ultrasonography
Background:
- Fetal choroid plexus cysts are frequently detected during routine prenatal ultrasounds.
- These cysts have been anecdotally linked to an increased risk of fetal chromosomal abnormalities.
Purpose of the Study:
- To evaluate the association between fetal choroid plexus cysts and chromosomal anomalies.
- To assess the diagnostic value of ultrasound-detected choroid plexus cysts in prenatal screening.
Main Methods:
- Retrospective analysis of 26 cases diagnosed with fetal choroid plexus cysts via ultrasonography between 1989-1991.
- Fetal karyotyping was performed in 21 cases to ascertain chromosomal status.
Main Results:
- One case (4.2%) out of 21 with ascertained karyotype showed trisomy 21.
- The study highlights the importance of detailed fetal morphology ultrasound, as structural anomalies increase trisomy 18 risk.
Conclusions:
- The presence of fetal choroid plexus cysts on ultrasound warrants consideration for prenatal diagnosis.
- The risk of chromosomal anomalies in fetuses with choroid plexus cysts is higher than the risk associated with advanced maternal age (35 years).