[Blood granulocyte priming in inflammation]

Metabolic activity of peripheral blood granulocytes during the development of inflammatory processes in animals (rats) was studied by chemiluminescence (CL) with luminol. Intensification of the CL- response of granulocytes during an acute inflammatory process induced by intravenous or intraperitoneal zymosan injection reflected the development of mononuclear infiltrative processes. No changes occurred in CL of circulating granulocytes in oxidative injury to the lungs of rats breathing pure oxygen, which was attended by increased infiltration of polynuclear cells.