[Histological structure of the testes in andropause]

A structure of the convoluted tubuli, spermatogenesis and number of Leydig's cells in the andropause have been analysed in dependence on the degree of symptoms intensity. A control group included otherwise healthy men with ++post-inflammatory azoospermia. A percentage of the convoluted tubuli with normal tissue (p < .002) and spermatogenesis (p < .001) has been significantly decreased in andropause. The number of Leydig's cells has not differed in andropause and in a control group (p < .05). No difference of significance have been noted in the structure of convoluted tubuli, spermatogenesis, and Leydig's cells number depending on the intensity of symptoms. FSH and LH levels have been significantly increased in andropause (p < .001). No relationship between FSH and LH levels and percentage of the abnormal convoluted tubuli has been observed. However there have been a relationship between FSH and LH levels and the number of abnormal convoluted tubuli with spermatogenesis inhibition and intensified clinical symptoms. There has also been a relationship between FSH and LH levels and Leydig's cells number in patients with marked symptoms of andropause.