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Lymphocyte-predominance Hodgkin's disease
1Department of Laboratory Medicine, Cross Cancer Institute, Edmonton, Alberta, Canada.
Seminars in Diagnostic Pathology
|November 1, 1992
Abstract:
Nodular lymphocyte-predominance Hodgkin's disease (NLPHD) has emerged as a distinct entity. It has a precursor lesion, known as follicular hyperplasia with progressively transformed germinal centers (PTGC), and a late stage consisting of transformation to a large cell lymphoma. All cellular components of NLPHD are derived from follicles, but so far no clonal population has been identified.