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Sleep patterns in acute ischemic stroke.

F Giubilei1, M Iannilli, A Vitale

  • 1Department of Neurological Sciences, University of Rome, La Sapienza, Italy.

Acta Neurologica Scandinavica
|December 1, 1992
PubMed
Summary
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Ischemic stroke patients show reduced REM sleep phases during the acute phase. This reduction, detected via polysomnography, correlates with stroke severity and lesion location, aiding outcome prediction.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Neuroscience

Background:

  • Ischemic stroke, particularly in the middle cerebral artery territory, can impact various physiological functions.
  • Sleep disturbances are common in neurological conditions, but their specific role in acute ischemic stroke requires further elucidation.

Purpose of the Study:

  • To investigate polysomnographic findings in patients during the acute phase of ischemic stroke.
  • To determine if sleep parameters, specifically REM sleep, correlate with neurological deficit severity and lesion characteristics.
  • To assess the utility of polysomnography in predicting clinical outcomes in acute ischemic stroke.

Main Methods:

  • Polysomnographic recordings using the Oxford Medilog 9000 System were performed on 18 ischemic stroke patients.

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  • Recordings were initiated within 5 hours of symptom onset and continued for three nights.
  • Neurologic examination, brain CT scans, and clinical/polysomnographic follow-up at 3 weeks were conducted.

    • Main Results:

    • A significant reduction in the number and duration of REM (Rapid Eye Movement) sleep phases was observed during the acute phase of ischemic stroke.
    • This reduction in REM sleep correlated significantly with the severity of the neurological deficit at the 3-week follow-up.
    • The extent of REM sleep reduction also showed a correlation with the anatomical site of the ischemic lesion identified on CT scans.

    Conclusions:

    • Polysomnography is a valuable tool for detecting sleep alterations in the acute phase of ischemic stroke.
    • Reduced REM sleep duration and frequency are associated with poorer neurological outcomes and specific lesion locations.
    • These findings suggest polysomnography can aid in assessing patient prognosis following an ischemic stroke.