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Influence of ceftriaxone on emergence of Clostridium difficile
T Lejko-Zupanc1, J Zakelj, F Strle
1Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva.
Antimicrobial Agents and Chemotherapy
|December 1, 1992
Abstract:
The influence of long-term ceftriaxone administration on the emergence of Clostridium difficile was studied with 80 patients receiving ceftriaxone for 14 days. In five patients (6.3%) C. difficile was cultured. The appearance of gastrointestinal disturbances during treatment with ceftriaxone was common, but the rate of emergence of C. difficile in immunocompetent patients was not high.