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Modification of RBC properties by an autoantibody. Binding to RBC senescent antigen
R Gareau1, G R Brisson, J Dubé
1Université du Québec à Trois-Rivières, Québec, Canada.
Cellular and Molecular Biology (Noisy-Le-Grand, France)
|August 1, 1992
Abstract:
It has been reported that natural antibodies alter aging RBCs, so increasing their vulnerability for removal from the blood stream. Results presented indicate that binding of anti-Gal, a natural antibody, to erythrocytes increases RBC rigidity in terms of microviscosity and deformability. Removal of RBCs from circulation could, at least in part, depend on these alterations.