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Polycythaemia after myeloid metaplasia with fibrosis: an unusual sequence
J Gardais1, S Suraniti, P Fressinaud
1Laboratoire de cyto-hématologie, Centre Départemental de Transfusion Sanguine d'Angers, France.
Haematologica
|September 1, 1992
Abstract:
In November 1981, a 77-yr-old woman consulted for myeloid metaplasia with fibrosis. A persistent hyperleucocytosis was treated with hydroxyurea from March, 1985 to March, 1989. At that time facial dyskinesia and polycythaemia developed. Investigations revealed a regression of myelofibrosis and a predominance of myeloid metaplasia in the liver. The mechanism of this event, rarely observed in myeloproliferative syndromes, is discussed in this new case.