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Related Experiment Videos

Esophagogastrectomy: a consecutive single-center series.

C J de Gara1, J J Payne-James, D B Silk

  • 1Department of Surgery, Central Middlesex Hospital, London, U.K.

Hepato-Gastroenterology
|December 1, 1992
PubMed
Summary
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Surgery for esophageal and upper gastric cancers showed similar 30-day mortality across procedures. Esophagectomy offered a survival advantage over unresectable lesions, but not over total gastrectomy.

Area of Science:

  • Surgical Oncology
  • Gastrointestinal Surgery
  • Thoracic Surgery

Background:

  • Esophageal and upper gastric malignancies require surgical intervention.
  • Surgical outcomes and survival rates for these cancers vary.
  • Optimizing surgical approaches is crucial for patient prognosis.

Purpose of the Study:

  • To evaluate the outcomes of surgical procedures for esophageal and upper gastric cancer.
  • To compare the 30-day operative mortality and survival rates between different surgical approaches.
  • To identify factors influencing survival in patients with these malignancies.

Main Methods:

  • A 7-year consecutive series of 140 patients undergoing surgery for esophageal or upper gastric malignancy.
  • Data collected included patient demographics, surgical procedures (esophagectomy, thoraco-abdominal gastrectomy), unresectable cases, and follow-up.

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  • Statistical analysis compared operative mortality and survival rates between groups.

    • Main Results:

    • No significant difference in 30-day operative mortality among esophagectomy (5%), thoraco-abdominal gastrectomy (10.8%), and unresectable cases (11.5%).
    • One-year survival rates were 33.4% for esophagectomy, 37.5% for total gastrectomy, and 6% for unresectable lesions.
    • Esophagectomy demonstrated a significant survival advantage compared to unresectable tumors (p < 0.05).

    Conclusions:

    • Surgical interventions for esophageal and upper gastric cancer have comparable short-term mortality.
    • Esophagectomy provides a survival benefit over unresectable disease, though not significantly different from total gastrectomy.
    • Patient factors like age and initial presentation parameters did not correlate with survival.