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Bacteriuria in patients with cirrhosis
M Rabinovitz1, M Prieto, J S Gavaler
1Department of Medicine, University of Pittsburgh, School of Medicine, PA.
Journal of Hepatology
|September 1, 1992
Summary
Bacteriuria, a urinary tract infection, is common in advanced liver disease patients, affecting 18%. This infection is more prevalent in females than males and is not linked to liver disease severity or patient age.
Area of Science:
- Urology
- Hepatology
- Infectious Diseases
Background:
- Cirrhosis of the liver is a serious condition that can lead to various complications.
- Bacteriuria, the presence of bacteria in urine, is a potential complication that requires investigation.
Purpose of the Study:
- To determine the prevalence and bacteriology of bacteriuria in patients with cirrhosis.
- To compare bacteriuria rates between genders and across different categories of cirrhosis.
Main Methods:
- A cohort of 140 patients with cirrhosis undergoing evaluation for liver transplantation were studied.
- Urine samples were collected within 24 hours of admission and cultured for bacterial growth.
Main Results:
- Significant bacteriuria (SB) was detected in 18% of patients, with E. coli and coagulase-negative staphylococcus being the most common pathogens.
- SB was significantly more common in females (32%) than in males (4%).
- Bacteriuria prevalence did not correlate with liver disease severity or patient age.
Conclusions:
- Bacteriuria is a common finding in patients with advanced liver disease, occurring in approximately 20% of cases.
- Female patients with cirrhosis exhibit a higher incidence of bacteriuria compared to males.
- The prevalence of bacteriuria in primary biliary cirrhosis is comparable to other forms of chronic advanced liver disease.