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Hematologic disorders in pregnancy.

K G Perry1, J C Morrison

  • 1Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson.

Obstetrics and Gynecology Clinics of North America
|December 11, 1992
PubMed
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Hematologic disorders during pregnancy are common, requiring established management for optimal perinatal outcomes. Prenatal diagnostics now enable in utero diagnosis for inherited conditions, aiding genetic counseling.

Area of Science:

  • Obstetrics and Gynecology
  • Hematology

Background:

  • Hematologic disorders are frequently encountered during pregnancy.
  • Management strategies for most conditions are established, but controversies persist for specific diseases like sickle cell disease and immune thrombocytopenia (ITP).

Purpose of the Study:

  • To outline the management of hematologic disorders in pregnancy.
  • To highlight the role of advanced prenatal diagnostics.

Main Methods:

  • Review of established treatment and obstetric management protocols for common hematologic disorders.
  • Discussion of current controversies in managing specific conditions.
  • Integration of recent advances in prenatal diagnostic techniques.

Main Results:

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  • Therapy is primarily directed at improving perinatal outcomes once a diagnosis is confirmed.
  • Prenatal diagnostic techniques facilitate in utero diagnosis for many inherited hematologic disorders.

    • Conclusions:

    • Established management protocols exist for most hematologic disorders in pregnancy.
    • Advances in prenatal diagnosis improve the feasibility of in utero diagnosis and genetic counseling for inherited conditions.