Study of the possible crossed reactivity between D. pteronyssinus and non pyroglyphide acarus. 1. Skin tests and FAST...

On 132 patients with case history of rhinitis and/or asthma in a domestic environment and with positive cutaneous tests contrasted with D. pteronyssinus, we have made cutaneous tests compared to said antigen and compared with D. farinae, L. destructor and A. siro, with extracts 5000 E/ml (Noon Units), as well as FAST inhibition, using D. pteronyssinus in its solid phase and all the above mentioned extracts in their liquid phase. Our results show that the frequency of D. pteronyssinus positivities in prick is greater than the other mites as well as the intensity of the response expressed in the size of the wheal showing significant differences between those found for D. pteronyssinus and those obtained with other mites. In turn those obtained with the D. farinae are significantly greater than those obtained with non-pyroglyphide mites. In FAST inhibition we only found a good correlation for D. pteronyssinus-D. pteronyssinus and D. pteronyssinus-D. farinae and there is no good correlation between the other mites. The correlation coefficients differ significantly except for those of the pyroglyphides, and the regression equations show a lack of parallelism in the regression lines. Consequently, on the basis of this study, we conclude that there is no crossed reactivity between D. peteronyssinus and non-pyroglyphide mites.